| Gene Information | |
|---|---|
| Gene Name | SLC45A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 782 |
| Protein Names | Proton-associated sugar transporter A (PAST-A) (Deleted in neuroblastoma 5 protein) (DNb-5) (Solute carrier family 45 member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000162426 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y2W3 |
| Gene Card | SLC45A1 |
| Uniprot ID | Q9Y2W3 |
| Pfam | PF07690 |
| In ASD | no |
| Allosteric Prediction | no (-0.983693289) |
| Ortholog in Animals | Alpaca_ SLC45A1 ( ortholog_one2one ) Dog_ SLC45A1 ( ortholog_one2one ) GuineaPig_ SLC45A1 ( ortholog_one2one ) Macaque_ SLC45A1 ( ortholog_one2one ) Mouse_ Slc45a1 ( ortholog_one2one ) Pig_ SLC45A1 ( ortholog_one2one ) Rat_ Slc45a1 ( ortholog_one2one ) Rabbit_ SLC45A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC45A4, SLC45A2, SLC45A3 |
| Tissue | NA |
| Tissue Specificity | Expressed in adult heart, brain, muscle and kidney, with very strong expression in brain. Also expressed in fetal brain, kidney and lung. {ECO:0000269|PubMed:10729226}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs141816307 rs781036625 rs150539474 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:28434495}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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