| Gene Information | |
|---|---|
| Gene Name | HCLS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 486 |
| Protein Names | Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000180353 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P14317 |
| Gene Card | HCLS1 |
| Uniprot ID | P14317 |
| Pfam | PF02218; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-0.343880459) |
| Ortholog in Animals | Alpaca_ HCLS1 ( ortholog_one2one ) Dog_ HCLS1 ( ortholog_one2one ) GuineaPig_ HCLS1 ( ortholog_one2one ) Macaque_ HCLS1 ( ortholog_one2one ) Mouse_ Hcls1 ( ortholog_one2one ) Pig_ HCLS1 ( ortholog_one2one ) Rat_ Hcls1 ( ortholog_one2one ) Rabbit_ HCLS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | COTL1, CTTN, DBNL, DBN1 |
| Tissue | NA |
| Tissue Specificity | Expressed only in tissues and cells of hematopoietic origin. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2070179 rs2070180 rs9869984 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:7682714}; Peripheral membrane protein {ECO:0000269|PubMed:7682714}. Cytoplasm {ECO:0000269|PubMed:7682714}. Mitochondrion {ECO:0000305|PubMed:7682714}. |
| Mouse PG classification | NA |
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