| Gene Information | |
|---|---|
| Gene Name | DCLK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 766 |
| Protein Names | Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2) |
| Target Name | serine/threonine-protein kinase dclk2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000170390 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8N568 |
| Gene Card | DCLK2 |
| Uniprot ID | Q8N568 |
| Pfam | PF03607; PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.428924749) |
| Ortholog in Animals | Alpaca_ DCLK2 ( ortholog_one2one ) Dog_ DCLK2 ( ortholog_one2one ) GuineaPig_ DCLK2 ( ortholog_one2one ) Macaque_ DCLK2 ( ortholog_one2one ) Mouse_ Dclk2 ( ortholog_one2one ) Pig_ DCLK2 ( ortholog_one2one ) Rat_ Dclk2 ( ortholog_one2one ) Rabbit_ DCLK2 ( ortholog_one2one ) |
| Ohnologs | DCX, DCLK1 |
| Paralogs | DCLK3, PHKG1, MYLK4, CAMKK1, CAMKK2, PSKH1, PNCK, CAMK1D, CAMKV, CAMK2B, CAMK1, STK11, STK33, PHKG2, DCLK1, PSKH2, CAMK2G, MYLK2, CAMK2D, CAMK2A, MYLK3, CAMK1G |
| Tissue | brain, heart |
| Tissue Specificity | Expressed in the brain, heart and eyes. {ECO:0000269|PubMed:18075264}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs56327537 rs759398144 rs34386880 rs35745104 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. {ECO:0000250}. |
| Mouse PG classification | NA |
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