| Gene Information | |
|---|---|
| Gene Name | HESX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 185 |
| Protein Names | Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000163666 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UBX0 |
| Gene Card | HESX1 |
| Uniprot ID | Q9UBX0 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-0.938274463) |
| Ortholog in Animals | Alpaca_ HESX1 ( ortholog_one2one ) Dog_ HESX1 ( ortholog_one2one ) GuineaPig_ HESX1 ( ortholog_one2one ) Macaque_ HESX1 ( ortholog_one2one ) Mouse_ Hesx1 ( ortholog_one2one ) Pig_ HESX1 ( ortholog_one2one ) Rat_ Hesx1 ( ortholog_one2one ) Rabbit_ HESX1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2K40 (NMR - ) |
| DBSNP | rs121909173 rs28936416 rs768165720 rs9878928 rs104893742 rs28936702 rs28936703 rs28936704 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:26781211}. |
| Mouse PG classification | NA |
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