Gene Information
Gene NameHES6
OrganismHomo sapiens (Human)
Gene Length224
Protein NamesTranscription cofactor HES-6 (C-HAIRY1) (Class B basic helix-loop-helix protein 41) (bHLHb41) (Hairy and enhancer of split 6)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000144485 )
Evolutionary StageEumetazoa
AlphaFoldDBQ96HZ4
Gene CardHES6
Uniprot IDQ96HZ4
PfamPF07527; PF00010
In ASDno
Allosteric Predictionno (-1.154397364)
Ortholog in AnimalsAlpaca_ HES6 ( ortholog_one2one )
Dog_ HES6 ( ortholog_one2one )
GuineaPig_ HES6 ( ortholog_one2one )
Macaque_ HES6 ( ortholog_one2one )
Mouse_ Hes6 ( ortholog_one2one )
Pig_ HES6 ( ortholog_one2one )
Rat_ Hes6 ( ortholog_one2one )
OhnologsNA
ParalogsHEYL, BHLHE40, HES5, HES4, HES7, HES3, HEY2, HEY1, HES2, HES1, HELT, BHLHE41
Tissuebrain
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3739061 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
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