| Gene Information | |
|---|---|
| Gene Name | CLDN5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 218 |
| Protein Names | Claudin-5 (Transmembrane protein deleted in VCFS) (TMDVCF) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000184113 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O00501 |
| Gene Card | CLDN5 |
| Uniprot ID | O00501 |
| Pfam | PF00822 |
| In ASD | no |
| Allosteric Prediction | no (-0.561106784) |
| Ortholog in Animals | Dog_ CLDN5 ( ortholog_one2one ) GuineaPig_ CLDN5 ( ortholog_one2one ) Macaque_ CLDN5 ( ortholog_one2one ) Mouse_ Cldn5 ( ortholog_one2one ) Pig_ CLDN5 ( ortholog_one2one ) Rat_ Cdc45 ( ortholog_one2one ) |
| Ohnologs | CLDN7, CLDN6, CLDN9 |
| Paralogs | CLDN1, CLDN8, CLDN3, CLDN20, CLDN11, CLDN14, CLDN18, CLDN7, CLDN10, CLDN9, CLDN17, CLDN24, CLDN22, CLDN23, CLDN4, CLDN15, CLDN19, CLDN34, CLDN2, CLDN25, CLDN16, CLDN6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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