Gene Information
Gene NameHES4
OrganismHomo sapiens (Human)
Gene Length221
Protein NamesTranscription factor HES-4 (hHES4) (Class B basic helix-loop-helix protein 42) (bHLHb42) (Hairy and enhancer of split 4) (bHLH factor Hes4)
Target NameNA
Target TypeNA
Gene Age55 ( ENSG00000188290 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9HCC6
Gene CardHES4
Uniprot IDQ9HCC6
PfamPF07527; PF00010
In ASDno
Allosteric Predictionno (-1.413995546)
Ortholog in AnimalsAlpaca_ HES4 ( ortholog_one2many )
Dog_ HES4 ( ortholog_one2one )
Macaque_ HES4 ( ortholog_one2one )
Pig_ HES4 ( ortholog_one2one )
OhnologsHES1
ParalogsHEYL, BHLHE40, HES5, HES7, HES3, HEY2, HEY1, HES2, HES1, HELT, HES6, BHLHE41
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
Mouse PG classificationNA
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