Gene Information
Gene NameHES3
OrganismHomo sapiens (Human)
Gene Length186
Protein NamesTranscription factor HES-3 (Class B basic helix-loop-helix protein 43) (bHLHb43) (Hairy and enhancer of split 3)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000173673 )
Evolutionary StageMammalia
AlphaFoldDBQ5TGS1
Gene CardHES3
Uniprot IDQ5TGS1
PfamPF00010
In ASDno
Allosteric Predictionno (-1.569838506)
Ortholog in AnimalsAlpaca_ HES3 ( ortholog_one2one )
Dog_ HES3 ( ortholog_one2one )
GuineaPig_ HES3 ( ortholog_one2one )
Macaque_ HES3 ( ortholog_one2one )
Mouse_ Hes3 ( ortholog_one2one )
Pig_ HES3 ( ortholog_one2one )
Rat_ Hes3 ( ortholog_one2one )
OhnologsNA
ParalogsHEYL, BHLHE40, HES5, HES4, HES7, HEY2, HEY1, HES2, HES1, HELT, HES6, BHLHE41
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Mouse PG classificationNA
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