| Gene Information | |
|---|---|
| Gene Name | PIXB |
| Organism | Homo sapiens (Human) |
| Gene Length | 803 |
| Protein Names | Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14155 |
| Gene Card | ARHGEF7 |
| Uniprot ID | Q14155 |
| Pfam | PF00307; PF00169; PF00621; PF07653 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BY1 (NMR - ) 1ZSG (NMR - ) 2L3G (NMR - ) 5SXP (X-ray 1.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell junction, focal adhesion {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Note=Detected at cell adhesions. A small proportion is detected at focal adhesions. |
| Mouse PG classification | NA |
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