| Gene Information | |
|---|---|
| Gene Name | PLXNC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1568 |
| Protein Names | Plexin-C1 (Virus-encoded semaphorin protein receptor) (CD antigen CD232) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000136040 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O60486 |
| Gene Card | PLXNC1 |
| Uniprot ID | O60486 |
| Pfam | PF08337; PF20170; PF01437; PF01833 |
| In ASD | no |
| Allosteric Prediction | no (-0.927334967) |
| Ortholog in Animals | Alpaca_ PLXNC1 ( ortholog_one2one ) Dog_ PLXNC1 ( ortholog_one2one ) GuineaPig_ PLXNC1 ( ortholog_one2one ) Macaque_ PLXNC1 ( ortholog_one2one ) Mouse_ Plxnc1 ( ortholog_one2one ) Pig_ PLXNC1 ( ortholog_one2one ) Rat_ Plxnc1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PLXNA3, PLXNA2, PLXNA1, PLXNA4, PLXNB2, PLXNB3, PLXNB1, PLXND1 |
| Tissue | whole.blood |
| Tissue Specificity | Detected in heart, brain, lung, spleen and placenta. {ECO:0000269|PubMed:9586637}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3KUZ (X-ray 2.30A ) 3NVN (X-ray 2.26A ) 3NVQ (X-ray 2.40A ) 6VXK (EM 3.10A ) |
| DBSNP | rs11107500 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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