| Gene Information | |
|---|---|
| Gene Name | BUB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 328 |
| Protein Names | Mitotic checkpoint protein BUB3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000154473 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43684 |
| Gene Card | BUB3 |
| Uniprot ID | O43684 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.654861211) |
| Ortholog in Animals | Alpaca_ BUB3 ( ortholog_one2one ) Dog_ PSTK ( ortholog_one2one ) GuineaPig_ BUB3 ( ortholog_one2one ) Macaque_ BUB3 ( ortholog_one2one ) Mouse_ Bub3 ( ortholog_one2one ) Pig_ BUB3 ( ortholog_one2one ) Rat_ Bub3 ( ortholog_one2one ) Rabbit_ BUB3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DNAAF10, RAE1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.031900(Mouse);0.002688(Rat);0.082762(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition. {ECO:0000250}. |
| Mouse PG classification | NA |
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