| Gene Information | |
|---|---|
| Gene Name | HERC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1050 |
| Protein Names | Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000138641 ) 544 ( ENSG00000287542 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15034 |
| Gene Card | HERC3 |
| Uniprot ID | Q15034 |
| Pfam | PF00632; PF00415 |
| In ASD | no |
| Allosteric Prediction | no (-0.356357967) |
| Ortholog in Animals | Alpaca_ HERC3 ( ortholog_one2one ) Dog_ HERC3 ( ortholog_one2one ) GuineaPig_ HERC3 ( ortholog_one2one ) Macaque_ HERC3 ( ortholog_one2one ) Mouse_ Herc3 ( ortholog_one2one ) Pig_ HERC3 ( ortholog_one2one ) Rat_ Herc3 ( ortholog_one2one ) Rabbit_ HERC3 ( ortholog_one2one ) |
| Ohnologs | HERC4 |
| Paralogs | HERC4, NEDD4, HECTD1, NEDD4L, UBE3B, HUWE1, SMURF1, AREL1, UBR5, HERC2, HECW2, WWP1, UBE3A, UBE3C, SMURF2, HACE1, HECTD2, HECTD4, ITCH, HECW1, WWP2, TRIP12, HERC5, HERC6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1804080 |
| Subcellular location [CC] | Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures. |
| Mouse PG classification | NA |
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