| Gene Information | |
|---|---|
| Gene Name | MAST4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2623 |
| Protein Names | Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000069020 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O15021 |
| Gene Card | MAST4 |
| Uniprot ID | O15021 |
| Pfam | PF08926; PF17820; PF02163; PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.004901624) |
| Ortholog in Animals | Alpaca_ MAST4 ( ortholog_one2one ) Dog_ MAST4 ( ortholog_one2one ) GuineaPig_ MAST4 ( ortholog_one2one ) Macaque_ MAST4 ( ortholog_one2one ) Mouse_ Mast4 ( ortholog_one2one ) Pig_ MAST4 ( ortholog_one2one ) Rat_ Mast4 ( ortholog_one2one ) Rabbit_ MAST4 ( ortholog_one2one ) |
| Ohnologs | MAST3, MAST1, MAST2 |
| Paralogs | STK32B, MAST3, STK32A, MAST2, LATS2, SGK1, SGK2, SGK3, LATS1, STK32C, MAST1, DMPK, MASTL |
| Tissue | NA |
| Tissue Specificity | Highly expressed in most normal human tissues, with an exception of in testis, small intestine, colon and peripheral blood leukocyte. {ECO:0000269|PubMed:17086981}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2W7R (X-ray 1.60A ) |
| DBSNP | rs6867856 rs752429440 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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