| Gene Information | |
|---|---|
| Gene Name | HEPACAM |
| Organism | Homo sapiens (Human) |
| Gene Length | 416 |
| Protein Names | Hepatocyte cell adhesion molecule (Protein hepaCAM) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000165478 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14CZ8 |
| Gene Card | HEPACAM |
| Uniprot ID | Q14CZ8 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.632319032) |
| Ortholog in Animals | Alpaca_ HEPACAM ( ortholog_one2one ) Dog_ HEPACAM ( ortholog_one2one ) GuineaPig_ HEPACAM ( ortholog_one2one ) Macaque_ HEPACAM ( ortholog_one2one ) Mouse_ Hepacam ( ortholog_one2one ) Pig_ HEPACAM ( ortholog_one2one ) Rat_ Hepacam ( ortholog_one2one ) Rabbit_ HEPACAM ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CEACAM4, CEACAM21, PSG1, CEACAM16, PSG8, PSG9, CEACAM7, PSG3, PSG7, CEACAM6, PSG11, CEACAM20, PSG2, PSG4, CEACAM1, CEACAM18, CEACAM8, CEACAM5, CEACAM3, PSG5, PSG6, CEACAM19, HEPACAM2, VSTM5 |
| Tissue | brain, cerebral.cortex, adipose.tissue, liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs387907054 rs387907053 rs387907050 rs387907055 rs387907052 rs1555055028 rs387907049 rs387907051 rs10790715 rs149782549 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15885354, ECO:0000269|PubMed:15917256}. Membrane; Single-pass type I membrane protein; Cytoplasmic side {ECO:0000269|PubMed:15885354, ECO:0000269|PubMed:15917256}. Note=In MCF-7 breast carcinoma and hepatic Hep 3B2.1-7 and Hep-G2 cell lines, localization of HEPACAM is cell density-dependent. In well spread cells, localized to punctate structures in the perinuclear membrane, cytoplasm, and at cell surface of protusions. In confluent cells, localized predominantly to the cytoplasmic membrane, particularly in areas of cell-cell contacts. Colocalizes with CDH1. |
| Mouse PG classification | NA |
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