Gene Information
Gene NameHENMT1
OrganismHomo sapiens (Human)
Gene Length393
Protein NamesSmall RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000162639 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ5T8I9
Gene CardHENMT1
Uniprot IDQ5T8I9
PfamNA
In ASDno
Allosteric Predictionno (-1.127522291)
Ortholog in AnimalsAlpaca_ HENMT1 ( ortholog_one2one )
Dog_ HENMT1 ( ortholog_one2one )
GuineaPig_ HENMT1 ( ortholog_one2one )
Macaque_ HENMT1 ( ortholog_one2one )
Mouse_ Henmt1 ( ortholog_one2one )
Pig_ HENMT1 ( ortholog_one2one )
Rat_ Henmt1 ( ortholog_one2one )
Rabbit_ HENMT1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuetestis
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4XCX  (X-ray  2.84A  5WY0  (X-ray  2.00A 
DBSNP rs9988420  rs35974434  rs17850887 
Subcellular location [CC]Cytoplasm {ECO:0000250|UniProtKB:Q568P9}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250|UniProtKB:Q568P9}.
Mouse PG classificationNA
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