| Gene Information | |
|---|---|
| Gene Name | HEM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1127 |
| Protein Names | Nck-associated protein 1-like (Hematopoietic protein 1) (Membrane-associated protein HEM-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P55160 |
| Gene Card | NCKAP1L |
| Uniprot ID | P55160 |
| Pfam | PF09735 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed only in cells of hematopoietic origin (PubMed:7643388, PubMed:1932118). Expressed in neutrophils (at protein level) (PubMed:16417406). Expressed in T-cells (at protein level) (PubMed:32647003). {ECO:0000269|PubMed:16417406, ECO:0000269|PubMed:1932118, ECO:0000269|PubMed:32647003, ECO:0000269|PubMed:7643388}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1956891911 rs770633648 rs750982844 rs7311877 rs2270581 rs1956961224 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16417406}; Single-pass membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:16417406}. Note=Localizes to the leading edge of polarized neutrophils. {ECO:0000269|PubMed:16417406, ECO:0000269|PubMed:17696648}. |
| Mouse PG classification | NA |
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