| Gene Information | |
|---|---|
| Gene Name | HELQ |
| Organism | Homo sapiens (Human) |
| Gene Length | 1101 |
| Protein Names | Helicase POLQ-like (EC 3.6.4.12) (Mus308-like helicase) (POLQ-like helicase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000163312 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8TDG4 |
| Gene Card | HELQ |
| Uniprot ID | Q8TDG4 |
| Pfam | PF00270; PF00271; PF20470 |
| In ASD | no |
| Allosteric Prediction | no (-0.969865427) |
| Ortholog in Animals | Alpaca_ HELQ ( ortholog_one2one ) GuineaPig_ HELQ ( ortholog_one2one ) Macaque_ HELQ ( ortholog_one2one ) Mouse_ Helq ( ortholog_one2one ) Pig_ HELQ ( ortholog_one2one ) Rat_ Helq ( ortholog_one2one ) Rabbit_ HELQ ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SKIV2L, SNRNP200, DDX60, DDX60L, ASCC3, MTREX, POLQ, HFM1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6831595 rs17006837 rs6817280 rs17006794 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21398521}. Chromosome {ECO:0000269|PubMed:21398521, ECO:0000269|PubMed:34937945}. Note=Localizes to sites of DNA damage; localizes to damaged replication forks. {ECO:0000269|PubMed:21398521, ECO:0000269|PubMed:34937945}. |
| Mouse PG classification | NA |
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