Gene Information
Gene NameHEL-S-13
OrganismHomo sapiens (Human)
Gene Length475
Protein NamesCytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A) (Threonyl dipeptidase)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96KP4
Gene CardCNDP2
Uniprot IDQ96KP4
PfamPF07687; PF01546
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue Specificity[Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568). {ECO:0000269|PubMed:12473676, ECO:0000269|PubMed:24395568}.;
[Isoform 2]: Broadly expressed in fetal tissues. Expressed in adult liver and placenta. {ECO:0000269|PubMed:17121880}.
Pharmacological Animal Models0.030997(Chimpanzee);NULL(Mouse);0.006101(Rat);0.020513(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4RUH  (X-ray  2.25A 
DBSNP rs2278161 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:12473676, ECO:0000269|PubMed:17121880}.
Mouse PG classificationNA
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