| Gene Information | |
|---|---|
| Gene Name | FBXL22 |
| Organism | Homo sapiens (Human) |
| Gene Length | 247 |
| Protein Names | F-box and leucine-rich protein 22 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000197361 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6P050 |
| Gene Card | FBXL22 |
| Uniprot ID | Q6P050 |
| Pfam | PF12937 |
| In ASD | no |
| Allosteric Prediction | no (-0.639707821) |
| Ortholog in Animals | Dog_ FBXL22 ( ortholog_one2one ) Macaque_ FBXL22 ( ortholog_one2one ) Mouse_ Fbxl22 ( ortholog_one2one ) Pig_ FBXL22 ( ortholog_one2one ) Rat_ Fbxl22 ( ortholog_one2one ) Rabbit_ FBXL22 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FBXL3, FBXL13, FBXL17, FBXL16, FBXL19, FBXL5, FBXL18, FBXL14, FBXL2, FBXL20, FBXL6, FBXL4, FBXL15, SKP2, FBXL7 |
| Tissue | endometrium, gall.bladder, heart, prostate, smooth.muscle, urinary.bladder |
| Tissue Specificity | Enriched in cardiac muscle. {ECO:0000269|PubMed:22972877}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8035931 |
| Subcellular location [CC] | Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:22972877}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |