| Gene Information | |
|---|---|
| Gene Name | NTSR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 410 |
| Protein Names | Neurotensin receptor type 2 (NT-R-2) (NTR2) (Levocabastine-sensitive neurotensin receptor) |
| Target Name | neurotensin receptor type 2 |
| Target Type | NA |
| Gene Age | 101 ( ENSG00000169006 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95665 |
| Gene Card | NTSR2 |
| Uniprot ID | O95665 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.469362213) |
| Ortholog in Animals | Alpaca_ NTSR2 ( ortholog_one2one ) Dog_ NTSR2 ( ortholog_one2one ) Macaque_ NTSR2 ( ortholog_one2one ) Mouse_ Ntsr2 ( ortholog_one2one ) Pig_ NTSR2 ( ortholog_one2one ) Rat_ Ntsr2 ( ortholog_one2one ) Rabbit_ NTSR2 ( ortholog_one2one ) |
| Ohnologs | NTSR1 |
| Paralogs | BRS3, NMBR, EDNRA, GRPR, EDNRB, GPR37, TRHR, GPR148, GPR37L1, NTSR1, GPR39, GHSR, MLNR, NMUR2, NMUR1 |
| Tissue | brain, cerebral.cortex, amygdala, caudate.nucleus, hippocampus, hypothalamus, nucleus.accumbens, putamen, substantia.nigra |
| Tissue Specificity | Expressed in prostate (at protein level). {ECO:0000269|PubMed:20048080}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6432225 rs34764121 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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