Gene Information
Gene NameHECTD2
OrganismHomo sapiens (Human)
Gene Length776
Protein NamesProbable E3 ubiquitin-protein ligase HECTD2 (EC 2.3.2.26) (HECT domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECTD2)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000165338 )
Evolutionary StageEukaryota
AlphaFoldDBQ5U5R9
Gene CardHECTD2
Uniprot IDQ5U5R9
PfamPF00632
In ASDno
Allosteric Predictionno (-0.432730049)
Ortholog in AnimalsAlpaca_ HECTD2 ( ortholog_one2one )
Dog_ HECTD2 ( ortholog_one2one )
GuineaPig_ HECTD2 ( ortholog_one2one )
Macaque_ HECTD2 ( ortholog_one2one )
Mouse_ Hectd2 ( ortholog_one2one )
Pig_ HECTD2 ( ortholog_one2one )
Rat_ Hectd2 ( ortholog_one2one )
Rabbit_ HECTD2 ( ortholog_one2one )
OhnologsUBE3A
ParalogsHERC4, NEDD4, HECTD1, NEDD4L, UBE3B, HUWE1, SMURF1, AREL1, UBR5, HERC2, HECW2, HERC3, WWP1, UBE3A, UBE3C, SMURF2, HACE1, HECTD4, ITCH, HECW1, WWP2, TRIP12, HERC5, HERC6
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs7081569 
Subcellular location [CC]NA
Mouse PG classificationNA
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