Gene Information
Gene NameTRIP11
OrganismHomo sapiens (Human)
Gene Length1979
Protein NamesThyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000100815 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ15643
Gene CardTRIP11
Uniprot IDQ15643
PfamNA
In ASDno
Allosteric Predictionno (-1.264817831)
Ortholog in AnimalsAlpaca_ TRIP11 ( ortholog_one2one )
Dog_ TRIP11 ( ortholog_one2one )
GuineaPig_ TRIP11 ( ortholog_one2one )
Macaque_ TRIP11 ( ortholog_one2one )
Mouse_ Trip11 ( ortholog_one2one )
Pig_ TRIP11 ( ortholog_one2one )
Rat_ Trip11 ( ortholog_one2one )
Rabbit_ TRIP11 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighly expressed in pancreas, muscle, heart, testis, peripheral blood leukocytes, and in several leukemia cell lines. Detected at intermediate levels in placenta and kidney, and at low levels in brain and lung. Isoform 1 and isoform 2 are expressed in articular chondrocytes (PubMed:30728324). {ECO:0000269|PubMed:10189370, ECO:0000269|PubMed:30728324, ECO:0000269|PubMed:9373237}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17127898  rs1566863801  rs2273186  rs34699762  rs34967261  rs34805848  rs4619320  rs12884523  rs34839498  rs35007347  rs2273183  rs11851376  rs1566843321  rs1051340  rs141259390 
Subcellular location [CC]Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:10189370, ECO:0000269|PubMed:25473115};
Peripheral membrane protein {ECO:0000269|PubMed:10189370}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10189370}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:25473115}. Note=Associates with the ends of centrosome-nucleated microtubules.
Mouse PG classificationNA
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