Gene Information
Gene NameMLIP
OrganismHomo sapiens (Human)
Gene Length458
Protein NamesMuscular LMNA-interacting protein (Cardiac Isl1-interacting protein) (CIP) (Muscular-enriched A-type laminin-interacting protein)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000146147 )
Evolutionary StageMammalia
AlphaFoldDBQ5VWP3
Gene CardMLIP
Uniprot IDQ5VWP3
PfamPF15274
In ASDno
Allosteric Predictionno (-1.289111672)
Ortholog in AnimalsAlpaca_ MLIP ( ortholog_one2one )
Dog_ MLIP ( ortholog_one2one )
Macaque_ MLIP ( ortholog_one2one )
Mouse_ Mlip ( ortholog_one2one )
Pig_ MLIP ( ortholog_one2one )
Rat_ Mlip ( ortholog_one2one )
Rabbit_ MLIP ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissueheart, atrium, left.ventricle, skeletal.muscle, tibial.nerve
Tissue SpecificityPrimarily expressed in heart and skeletal muscle. Also detected in liver. {ECO:0000269|PubMed:21498514, ECO:0000269|PubMed:26436652}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17625497  rs4712056  rs6934690  rs2275769 
Subcellular location [CC]Nucleus {ECO:0000250|UniProtKB:Q5FW52}. Nucleus envelope {ECO:0000250|UniProtKB:Q5FW52}. Nucleus, PML body {ECO:0000250|UniProtKB:Q5FW52}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q5FW52};
Peripheral membrane protein {ECO:0000250|UniProtKB:Q5FW52};
Cytoplasmic side {ECO:0000250|UniProtKB:Q5FW52}.
Mouse PG classificationNA
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