| Gene Information | |
|---|---|
| Gene Name | GALNT15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 639 |
| Protein Names | Polypeptide N-acetylgalactosaminyltransferase 15 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 2) (GalNAc-T-like protein 2) (pp-GaNTase-like protein 2) (Polypeptide N-acetylgalactosaminyltransferase-like protein 2) (Protein-UDP acetylgalactosaminyltransferase-like protein 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000131386 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8N3T1 |
| Gene Card | GALNT15 |
| Uniprot ID | Q8N3T1 |
| Pfam | PF00535; PF00652 |
| In ASD | no |
| Allosteric Prediction | no (-1.035152909) |
| Ortholog in Animals | Alpaca_ GALNT15 ( ortholog_one2one ) Dog_ GALNT15 ( ortholog_one2one ) GuineaPig_ GALNT15 ( ortholog_one2one ) Macaque_ GALNT15 ( ortholog_one2one ) Mouse_ Galnt15 ( ortholog_one2one ) Pig_ GALNT15 ( ortholog_one2one ) Rat_ Galnt15 ( ortholog_one2one ) Rabbit_ GALNT15 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GALNT11, GALNT10, GALNTL6, GALNT1, GALNT16, GALNTL5, GALNT18, GALNT2, GALNT13, GALNT9, GALNT14, GALNT17, GALNT7, GALNT12, GALNT6, GALNT8, GALNT5, GALNT3, GALNT4 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highly expressed in small intestine, placenta, spleen, cerebral cortex and ovary. Expressed at intermediate level in uterus, mammary gland, stomach, cerebellum and whole brain. Weakly expressed in fetal brain, bone marrow, thyroid gland, thymus, heart, skeletal muscle, lung, liver, colon, pancreas, kidney and testis. Not expressed in leukocyte. Expressed in both normal and osteoarthritic cartilage. Expressed at low level in chondrocytes in all zones of both normal and osteoarthritic cartilage. {ECO:0000269|PubMed:11597177, ECO:0000269|PubMed:15147861}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs36026882 rs11715981 rs12634179 rs17851238 rs2271077 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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