Gene Information
Gene NameHDDC3
OrganismHomo sapiens (Human)
Gene Length179
Protein NamesGuanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000184508 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ8N4P3
Gene CardHDDC3
Uniprot IDQ8N4P3
PfamNA
In ASDno
Allosteric Predictionno (-0.726408158)
Ortholog in AnimalsAlpaca_ HDDC3 ( ortholog_one2one )
Dog_ HDDC3 ( ortholog_one2one )
GuineaPig_ HDDC3 ( ortholog_one2one )
Macaque_ HDDC3 ( ortholog_one2one )
Mouse_ Hddc3 ( ortholog_one2one )
Pig_ HDDC3 ( ortholog_one2one )
Rat_ Hddc3 ( ortholog_one2one )
Rabbit_ HDDC3 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022642(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3NR1  (X-ray  1.90A  5VXA  (X-ray  2.10A 
DBSNP NA 
Subcellular location [CC]NA
Mouse PG classificationNA
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