| Gene Information | |
|---|---|
| Gene Name | HDC |
| Organism | Homo sapiens (Human) |
| Gene Length | 662 |
| Protein Names | Histidine decarboxylase (HDC) (EC 4.1.1.22) |
| Target Name | histidine decarboxylase |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000140287 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P19113 |
| Gene Card | HDC |
| Uniprot ID | P19113 |
| Pfam | PF00282 |
| In ASD | no |
| Allosteric Prediction | yes (0.098319663) |
| Ortholog in Animals | Alpaca_ HDC ( ortholog_one2one ) Dog_ HDC ( ortholog_one2one ) GuineaPig_ HDC ( ortholog_one2one ) Macaque_ HDC ( ortholog_one2one ) Mouse_ Hdc ( ortholog_one2one ) Pig_ HDC ( ortholog_one2one ) Rat_ Hdc ( ortholog_one2one ) Rabbit_ HDC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SGPL1, CSAD, DDC, PDXDC1, GAD1, GADL1, GAD2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4E1O (X-ray 1.80A ) 7EIW (X-ray 2.10A ) 7EIX (X-ray 1.90A ) 7EIY (X-ray 2.20A ) |
| DBSNP | rs17740607 rs1353958864 rs16963486 rs2073440 |
| Subcellular location [CC] | NA |
| Mouse PG classification | LPG |
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