| Gene Information | |
|---|---|
| Gene Name | HDC |
| Organism | Homo sapiens (Human) |
| Gene Length | 543 |
| Protein Names | Headcase protein homolog (hHDC) |
| Target Name | histidine decarboxylase |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000140287 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9UBI9 |
| Gene Card | HECA |
| Uniprot ID | Q9UBI9 |
| Pfam | PF16002; PF15353 |
| In ASD | no |
| Allosteric Prediction | yes (0.098319663) |
| Ortholog in Animals | Alpaca_ HDC ( ortholog_one2one ) Dog_ HDC ( ortholog_one2one ) GuineaPig_ HDC ( ortholog_one2one ) Macaque_ HDC ( ortholog_one2one ) Mouse_ Hdc ( ortholog_one2one ) Pig_ HDC ( ortholog_one2one ) Rat_ Hdc ( ortholog_one2one ) Rabbit_ HDC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SGPL1, CSAD, DDC, PDXDC1, GAD1, GADL1, GAD2 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined. Highest levels are in the spleen, thymus, peripheral blood and heart. Lowest in the kidney and pancreas. {ECO:0000269|PubMed:11696983}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | LPG |
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