Gene Information
Gene NameZP4
OrganismHomo sapiens (Human)
Gene Length540
Protein NamesZona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4]
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000116996 )
Evolutionary StageVertebrata
AlphaFoldDBQ12836
Gene CardZP4
Uniprot IDQ12836
PfamPF00088; PF00100
In ASDno
Allosteric Predictionno (-0.429390071)
Ortholog in AnimalsAlpaca_ ZP4 ( ortholog_one2one )
Dog_ ZP4 ( ortholog_one2one )
Macaque_ ZP4 ( ortholog_one2one )
Pig_ ZP4 ( ortholog_one2one )
Rat_ Zp4 ( ortholog_one2one )
Rabbit_ ZP4 ( ortholog_one2one )
OhnologsNA
ParalogsQRICH2, ZP1, C16orf96, ZP2
TissueNA
Tissue SpecificityExpressed in oocytes.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34370253  rs34811980 
Subcellular location [CC][Processed zona pellucida sperm-binding protein 4]: Zona pellucida {ECO:0000250|UniProtKB:Q00193}.;
Cell membrane {ECO:0000250|UniProtKB:Q00193};
Single-pass type I membrane protein {ECO:0000255}.
Mouse PG classificationNA
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