| Gene Information | |
|---|---|
| Gene Name | HDAC9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1011 |
| Protein Names | Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR) |
| Target Name | histone deacetylase |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000048052 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UKV0 |
| Gene Card | HDAC9 |
| Uniprot ID | Q9UKV0 |
| Pfam | PF12203; PF00850 |
| In ASD | no |
| Allosteric Prediction | yes (0.729848021) |
| Ortholog in Animals | Alpaca_ HDAC9 ( ortholog_one2one ) Dog_ HDAC9 ( ortholog_one2one ) GuineaPig_ HDAC9 ( ortholog_one2one ) Macaque_ HDAC9 ( ortholog_one2one ) Mouse_ Hdac9 ( ortholog_one2one ) Pig_ HDAC9 ( ortholog_one2one ) Rat_ Hdac9 ( ortholog_one2one ) Rabbit_ HDAC9 ( ortholog_one2one ) |
| Ohnologs | HDAC7, HDAC5, HDAC4 |
| Paralogs | HDAC4, HDAC11, HDAC8, HDAC3, HDAC7, HDAC6, HDAC10, HDAC2, HDAC1, HDAC5 |
| Tissue | NA |
| Tissue Specificity | Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level). {ECO:0000269|PubMed:10655483, ECO:0000269|PubMed:11535832, ECO:0000269|PubMed:12590135, ECO:0000269|PubMed:12706107}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1333490692 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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