| Gene Information | |
|---|---|
| Gene Name | SERPINB7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 380 |
| Protein Names | Serpin B7 (Megsin) (TP55) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000166396 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O75635 |
| Gene Card | SERPINB7 |
| Uniprot ID | O75635 |
| Pfam | PF00079 |
| In ASD | no |
| Allosteric Prediction | no (-0.568052105) |
| Ortholog in Animals | Alpaca_ SERPINB7 ( ortholog_one2one ) Alpaca_ SERPINB7 ( ortholog_one2many ) Dog_ SERPINB7 ( ortholog_one2one ) Macaque_ SERPINB7 ( ortholog_one2one ) Mouse_ Serpinb7 ( ortholog_one2one ) Pig_ SERPINB7 ( ortholog_one2one ) Rat_ Serpinb7 ( ortholog_one2one ) Rabbit_ SERPINB7 ( ortholog_one2one ) |
| Ohnologs | SERPINA1 |
| Paralogs | SERPING1, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINA7, SERPINB8, SERPINA6, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINA12, SERPINE1, SERPINF2, SERPINA4, SERPINB11, SERPINB5, SERPINB12, SERPINB9, SERPINE3, SERPINB4, SERPINB3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINA11, SERPINB2 |
| Tissue | skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Predominantly expressed in mesangial cells. Expressed in the epidermis of the whole body. {ECO:0000269|PubMed:24207119}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17782413 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |