| Gene Information | |
|---|---|
| Gene Name | HCN3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 774 |
| Protein Names | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000143630 ) 3 ( ENSG00000263324 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9P1Z3 |
| Gene Card | HCN3 |
| Uniprot ID | Q9P1Z3 |
| Pfam | PF00027; PF00520; PF08412 |
| In ASD | no |
| Allosteric Prediction | yes (0.426371525) |
| Ortholog in Animals | Alpaca_ HCN3 ( ortholog_one2one ) Dog_ HCN3 ( ortholog_one2one ) GuineaPig_ HCN3 ( ortholog_one2one ) Macaque_ HCN3 ( ortholog_one2one ) Mouse_ Hcn3 ( ortholog_one2one ) Pig_ HCN3 ( ortholog_one2one ) Rat_ Hcn3 ( ortholog_one2one ) Rabbit_ HCN3 ( ortholog_one2one ) |
| Ohnologs | HCN2, HCN4, HCN1 |
| Paralogs | KCNH7, KCNH1, CNGA3, KCNH3, HCN4, HCN2, KCNH8, HCN1, CNGB3, CNGB1, CNGA1, KCNH6, KCNH2, KCNH4, CNGA2, CNGA4, KCNH5 |
| Tissue | NA |
| Tissue Specificity | Detected in brain. {ECO:0000269|PubMed:16043489}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35001694 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16043489}; Multi-pass membrane protein {ECO:0000269|PubMed:16043489}. |
| Mouse PG classification | NA |
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