| Gene Information | |
|---|---|
| Gene Name | RPS6KC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1066 |
| Protein Names | Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000136643 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96S38 |
| Gene Card | RPS6KC1 |
| Uniprot ID | Q96S38 |
| Pfam | PF04212; PF00069; PF00787 |
| In ASD | no |
| Allosteric Prediction | no (-1.093387314) |
| Ortholog in Animals | Alpaca_ RPS6KC1 ( ortholog_one2one ) Dog_ RPS6KC1 ( ortholog_one2one ) GuineaPig_ RPS6KC1 ( ortholog_one2one ) Macaque_ RPS6KC1 ( ortholog_one2one ) Mouse_ Rps6kc1 ( ortholog_one2one ) Pig_ RPS6KC1 ( ortholog_one2one ) Rat_ Rps6kc1 ( ortholog_one2one ) Rabbit_ RPS6KC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SNX15, RPS6KL1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon. {ECO:0000269|PubMed:12077123}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs56087470 rs56032860 rs56369827 rs56183862 rs35281247 rs17020314 rs56060894 rs34080597 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12077123, ECO:0000269|PubMed:15750338}. Membrane {ECO:0000269|PubMed:12077123}. Early endosome {ECO:0000269|PubMed:15750338}. |
| Mouse PG classification | NA |
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