| Gene Information | |
|---|---|
| Gene Name | GLO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 184 |
| Protein Names | Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase) |
| Target Name | lactoylglutathione lyase |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000124767 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q04760 |
| Gene Card | GLO1 |
| Uniprot ID | Q04760 |
| Pfam | PF00903 |
| In ASD | no |
| Allosteric Prediction | yes (0.109686638) |
| Ortholog in Animals | Alpaca_ GLO1 ( ortholog_one2one ) Dog_ GLO1 ( ortholog_one2one ) GuineaPig_ GLO1 ( ortholog_one2one ) Macaque_ GLO1 ( ortholog_one2one ) Mouse_ Glo1 ( ortholog_one2one ) Pig_ GLO1 ( ortholog_one2one ) Rat_ Glo1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GLOD4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BH5 (X-ray 2.20A ) 1FRO (X-ray 2.20A ) 1QIN (X-ray 2.00A ) 1QIP (X-ray 1.72A ) 3VW9 (X-ray 1.47A ) 3W0T (X-ray 1.35A ) 3W0U (X-ray 1.70A ) 7WSZ (X-ray 1.52A ) 7WT0 (X-ray 2.00A ) 7WT1 (X-ray 1.85A ) 7WT2 (X-ray 2.00A ) |
| DBSNP | rs17855424 rs4746 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
| click here to return to the previous page | |