| Gene Information | |
|---|---|
| Gene Name | HBP |
| Organism | Homo sapiens (Human) |
| Gene Length | 270 |
| Protein Names | Histone RNA hairpin-binding protein (Histone stem-loop-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14493 |
| Gene Card | SLBP |
| Uniprot ID | Q14493 |
| Pfam | PF15247 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:9049306}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KJM (NMR - ) 4L8R (X-ray 2.60A ) 4QOZ (X-ray 2.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12588979, ECO:0000269|PubMed:15829567}. Nucleus {ECO:0000269|PubMed:12588979, ECO:0000269|PubMed:15829567}. Note=Polyribosome-associated (PubMed:12588979). Localizes predominantly in the nucleus at the G1/G2 phases and the beginning of S phase (PubMed:12588979). Through the S phase, partially redistributes to the cytoplasm (PubMed:12588979). Binding to histone mRNA is necessary for cytoplasmic localization (PubMed:12588979). Shuttles between the nucleus and the cytoplasm (PubMed:15829567). Imported in the nucleus by the Importin alpha/Importin beta receptor (PubMed:15829567). {ECO:0000269|PubMed:12588979, ECO:0000269|PubMed:15829567}. |
| Mouse PG classification | NA |
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