Gene Information
Gene NameZC3H8
OrganismHomo sapiens (Human)
Gene Length291
Protein NamesZinc finger CCCH domain-containing protein 8
Target NameNA
Target TypeNA
Gene Age132 ( ENSG00000144161 )
Evolutionary StageEukaryota
AlphaFoldDBQ8N5P1
Gene CardZC3H8
Uniprot IDQ8N5P1
PfamPF00642
In ASDno
Allosteric Predictionno (-0.590727745)
Ortholog in AnimalsAlpaca_ ZC3H8 ( ortholog_one2one )
Dog_ ZC3H8 ( ortholog_one2one )
GuineaPig_ ZC3H8 ( ortholog_one2one )
Macaque_ ZC3H8 ( ortholog_one2one )
Mouse_ Zc3h8 ( ortholog_one2one )
Pig_ ZC3H8 ( ortholog_one2one )
Rat_ Zc3h8 ( ortholog_one2one )
Rabbit_ ZC3H8 ( ortholog_one2one )
OhnologsNA
ParalogsZC3H4, ZC3H6
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs35782954 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:23932780}. Note=Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.
Mouse PG classificationNA
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