Gene Information
Gene NameZNF224
OrganismHomo sapiens (Human)
Gene Length707
Protein NamesZinc finger protein 224 (Bone marrow zinc finger 2) (BMZF-2) (Zinc finger protein 233) (Zinc finger protein 255) (Zinc finger protein 27) (Zinc finger protein KOX22)
Target NameNA
Target TypeNA
Gene Age78 ( ENSG00000267680 )
Evolutionary StageMammalia
AlphaFoldDBQ9NZL3
Gene CardZNF224
Uniprot IDQ9NZL3
PfamPF01352; PF00096
In ASDno
Allosteric Predictionno (-0.819248653)
Ortholog in AnimalsAlpaca_ ZNF224 ( ortholog_one2one )
Macaque_ ZNF224 ( ortholog_one2one )
OhnologsNA
ParalogsZNF45, ZNF268, ZNF775, ZNF140, ZNF544, ZNF841, ZNF7, ZNF571, ZNF28, GLI4, ZNF732, ZNF595, ZNF718, ZNF493, ZNF117, ZNF141, ZNF607, ZNF484, ZFP3, ZNF790, ZNF540, ZNF286A, ZNF672, ZNF629, ZNF605, ZNF836, ZNF483, ZNF71, ZNF713, MZF1, ZNF460, ZNF517, ZNF585A, ZNF585B, ZNF157, ZNF16, ZNF621, ZNF354B, ZNF615, ZNF471, ZNF677, ZNF502, ZSCAN10, ZNF490, ZNF658, ZNF568, ZNF624, ZNF432, ZNF30, ZNF623, ZNF260, ZNF93, ZNF138, ZNF676, ZNF735, ZNF722, ZNF254, ZNF492, ZNF726, ZNF679, ZNF90, ZNF708, ZNF716, ZNF714, ZNF728, ZNF486, ZNF506, ZNF300, ZNF132, ZIM2, ZNF696, ZNF317, ZNF616, ZFP14, ZNF275, ZNF32, ZNF534, ZFP1, ZNF780A, ZNF182, ZNF234, ZNF782, ZFP28, ZIM3, ZKSCAN5, ZNF415, ZNF573, ZFP2, ZNF189, ZNF519, ZNF195, ZNF429, ZFP30, ZNF699, ZNF630, ZNF829, ZNF383, ZNF43, ZNF655, ZNF543, ZNF227, ZNF345, ZNF354A, ZNF37A, ZNF454, ZNF780B, ZNF267, ZNF814, ZNF2, ZNF226, ZNF546, ZNF331, ZNF283, ZNF628, ZNF565, ZNF879, ZNF74, ZNF311, ZNF501, ZNF3, ZKSCAN8P1, ZNF135, ZNF391, ZNF510, ZNF470, ZNF606, ZNF239, ZNF23, ZNF320, ZFP82, ZNF235, ZNF146, ZNF251, ZNF322, ZNF514, ZNF461, ZNF600, ZNF611, ZNF26, ZNF121, ZNF33A, ZNF33B, ZNF334, ZNF250, ZNF197, ZNF577, ZNF436, ZNF835, ZNF112, ZNF229, ZNF81, ZNF789, ZNF724, ZNF695, ZNF681, ZNF682, ZNF727, ZNF678, ZNF736, ZNF738, ZNF85, ZNF175, ZNF354C, ZNF41, ZNF717, ZNF528, ZNF880, ZNF83, RBAK, ZNF12, ZNF225, ZNF284, ZNF221
TissueNA
Tissue SpecificityUbiquitous. Mainly expressed in fetal tissues. {ECO:0000269|PubMed:12239212}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2ELY  (NMR  -  )  2ELZ  (NMR  -  )  2EM0  (NMR  -  )  2EM6  (NMR  -  )  2EM7  (NMR  -  )  2EM8  (NMR  -  )  2EM9  (NMR  -  )  2EN1  (NMR  -  )  2EN8  (NMR  -  )  2ENA  (NMR  -  )  2ENC  (NMR  -  )  2EOQ  (NMR  -  )  2EOR  (NMR  -  )  2EQ4  (NMR  -  )  2YSP  (NMR  -  )  2YTH  (NMR  -  ) 
DBSNP rs2068061  rs4239529  rs3208201  rs58935748  rs3746323  rs3746319 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:12239212, ECO:0000269|PubMed:20587513, ECO:0000269|PubMed:23665872}. Note=Colocalizes with DEPDC1A at the nucleus.
Mouse PG classificationNA
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