| Gene Information | |
|---|---|
| Gene Name | CDC20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 499 |
| Protein Names | Cell division cycle protein 20 homolog (p55CDC) |
| Target Name | cell division cycle protein 20 homolog |
| Target Type | Preclinical target |
| Gene Age | 1064 ( ENSG00000117399 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q12834 |
| Gene Card | CDC20 |
| Uniprot ID | Q12834 |
| Pfam | PF12894; PF00400 |
| In ASD | no |
| Allosteric Prediction | yes (0.57934859) |
| Ortholog in Animals | Alpaca_ CDC20 ( ortholog_one2one ) Dog_ CDC20 ( ortholog_one2one ) GuineaPig_ CDC20 ( ortholog_one2one ) Macaque_ CDC20 ( ortholog_one2one ) Mouse_ Cdc20 ( ortholog_one2one ) Pig_ CDC20 ( ortholog_one2one ) Rat_ Cdc20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CDC20B, FZR1 |
| Tissue | brain, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.358433(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4GGA (X-ray 2.04A ) 4GGC (X-ray 1.35A ) 4GGD (X-ray 2.44A ) 4N14 (X-ray 2.10A ) 5G04 (EM 4.00A ) 5KHR (EM 6.10A ) 5KHU (EM 4.80A ) 5LCW (EM 4.00A ) 6F0X (EM 4.60A ) 6Q6G (EM 3.20A ) 6Q6H (EM 3.20A ) |
| DBSNP | rs45443196 rs45461499 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20034488}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:20034488}. |
| Mouse PG classification | NA |
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