| Gene Information | |
|---|---|
| Gene Name | GRID2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1007 |
| Protein Names | Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000152208 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43424 |
| Gene Card | GRID2 |
| Uniprot ID | O43424 |
| Pfam | PF01094; PF00060; PF10613 |
| In ASD | no |
| Allosteric Prediction | yes (0.40900427) |
| Ortholog in Animals | Alpaca_ GRID2 ( ortholog_one2one ) Dog_ GRID2 ( ortholog_one2one ) GuineaPig_ GRID2 ( ortholog_one2one ) Macaque_ GRID2 ( ortholog_one2one ) Mouse_ Grid2 ( ortholog_one2one ) Pig_ GRID2 ( ortholog_one2one ) Rat_ Grid2 ( ortholog_one2one ) Rabbit_ GRID2 ( ortholog_one2one ) |
| Ohnologs | GRID1 |
| Paralogs | GRIN3A, GRIN2A, GRIK5, GRIN2C, GRID1, GRIK3, GRIN2D, GRIN1, GRIK4, GRIA3, GRIK1, GRIA2, GRIA1, GRIN3B, GRIK2, GRIA4, GRIN2B |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5KC8 (X-ray 1.75A ) 5KCA (X-ray 3.10A ) |
| DBSNP | rs34144324 rs34796082 rs10034345 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | HPG |
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