Gene Information
Gene NameHAPLN4
OrganismHomo sapiens (Human)
Gene Length402
Protein NamesHyaluronan and proteoglycan link protein 4 (Brain link protein 2)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000187664 )
Evolutionary StageVertebrata
AlphaFoldDBQ86UW8
Gene CardHAPLN4
Uniprot IDQ86UW8
PfamPF07686; PF00193
In ASDno
Allosteric Predictionno (-1.475366145)
Ortholog in AnimalsAlpaca_ HAPLN4 ( ortholog_one2one )
Dog_ HAPLN4 ( ortholog_one2one )
GuineaPig_ HAPLN4 ( ortholog_one2one )
Macaque_ HAPLN4 ( ortholog_one2one )
Mouse_ Hapln4 ( ortholog_one2one )
Pig_ HAPLN4 ( ortholog_one2one )
Rat_ Hapln4 ( ortholog_one2one )
OhnologsNA
ParalogsBCAN, HAPLN1, NCAN, ACAN, HAPLN3, VCAN, HAPLN2
TissueNA
Tissue SpecificityExpressed predominantly in brain. {ECO:0000269|PubMed:12663660}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q9ESM3}.
Mouse PG classificationNA
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