| Gene Information | |
|---|---|
| Gene Name | HAPLN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Hyaluronan and proteoglycan link protein 1 (Cartilage-linking protein 1) (Cartilage-link protein) (Proteoglycan link protein) |
| Target Name | hyaluronan and proteoglycan link protein 1 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000145681 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P10915 |
| Gene Card | HAPLN1 |
| Uniprot ID | P10915 |
| Pfam | PF07686; PF00193 |
| In ASD | no |
| Allosteric Prediction | no (-0.352875776) |
| Ortholog in Animals | Alpaca_ HAPLN1 ( ortholog_one2one ) Dog_ HAPLN1 ( ortholog_one2one ) GuineaPig_ HAPLN1 ( ortholog_one2one ) Macaque_ HAPLN1 ( ortholog_one2one ) Mouse_ Hapln1 ( ortholog_one2one ) Pig_ HAPLN1 ( ortholog_one2one ) Rat_ Hapln1 ( ortholog_one2one ) Rabbit_ HAPLN1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BCAN, NCAN, ACAN, HAPLN3, VCAN, HAPLN2, HAPLN4 |
| Tissue | placenta, mitral.valve |
| Tissue Specificity | Widely expressed. Weakly expressed in the brain. {ECO:0000269|PubMed:11027579, ECO:0000269|PubMed:12663660}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6864342 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix. |
| Mouse PG classification | NA |
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