| Gene Information | |
|---|---|
| Gene Name | ACAP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 778 |
| Protein Names | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000114331 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15057 |
| Gene Card | ACAP2 |
| Uniprot ID | Q15057 |
| Pfam | PF12796; PF01412; PF00169 |
| In ASD | no |
| Allosteric Prediction | no (-0.855109977) |
| Ortholog in Animals | Alpaca_ ACAP2 ( ortholog_one2one ) Dog_ ACAP2 ( ortholog_one2one ) GuineaPig_ ACAP2 ( ortholog_one2one ) Macaque_ ACAP2 ( ortholog_one2one ) Mouse_ Acap2 ( ortholog_one2one ) Pig_ ACAP2 ( ortholog_one2one ) Rat_ Acap2 ( ortholog_one2one ) Rabbit_ ACAP2 ( ortholog_one2one ) |
| Ohnologs | ACAP1, ACAP3 |
| Paralogs | ASAP2, ASAP1, ACAP3, ARAP2, GIT1, ARAP3, AGFG1, ADAP1, SMAP1, AGAP1, AGAP3, AGAP4, AGAP6, AGAP9, AGAP5, ARFGAP1, ASAP3, APPL1, ARFGAP2, ARAP1, AGFG2, APPL2, ARFGAP3, GIT2, ADAP2, SMAP2, AGAP2, ACAP1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highest level in lung. {ECO:0000269|PubMed:11062263}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6IF3 (X-ray 1.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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