| Gene Information | |
|---|---|
| Gene Name | STAC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 411 |
| Protein Names | SH3 and cysteine-rich domain-containing protein 2 (24b2/STAC2) (Src homology 3 and cysteine-rich domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000141750 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q6ZMT1 |
| Gene Card | STAC2 |
| Uniprot ID | Q6ZMT1 |
| Pfam | PF00130; PF14604 |
| In ASD | no |
| Allosteric Prediction | no (-1.794429958) |
| Ortholog in Animals | Alpaca_ STAC2 ( ortholog_one2one ) Dog_ STAC2 ( ortholog_one2one ) GuineaPig_ STAC2 ( ortholog_one2one ) Macaque_ STAC2 ( ortholog_one2one ) Mouse_ Stac2 ( ortholog_one2one ) Pig_ STAC2 ( ortholog_one2one ) Rat_ Stac2 ( ortholog_one2one ) Rabbit_ STAC2 ( ortholog_one2one ) |
| Ohnologs | STAC, STAC3 |
| Paralogs | STAC, STAC3 |
| Tissue | brain, cerebral.cortex, seminal.vesicle, vas.deferens |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6B26 (X-ray 1.20A ) 6B27 (X-ray 1.73A ) 6B28 (X-ray 2.55A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8R1B0}. Cell membrane {ECO:0000250|UniProtKB:Q8R1B0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8R1B0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8R1B0}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q8R1B0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8R1B0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8R1B0}. Note=Colocalizes with CACNA1C at the plasma membrane of transfected cells. {ECO:0000250|UniProtKB:Q8R1B0}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |