| Gene Information | |
|---|---|
| Gene Name | WNT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 360 |
| Protein Names | Protein Wnt-2 (Int-1-like protein 1) (Int-1-related protein) (IRP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000105989 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P09544 |
| Gene Card | WNT2 |
| Uniprot ID | P09544 |
| Pfam | PF00110 |
| In ASD | no |
| Allosteric Prediction | no (-0.197416666) |
| Ortholog in Animals | Alpaca_ WNT2 ( ortholog_one2one ) Dog_ WNT2 ( ortholog_one2one ) GuineaPig_ WNT2 ( ortholog_one2one ) Macaque_ WNT2 ( ortholog_one2one ) Mouse_ Wnt2 ( ortholog_one2one ) Pig_ WNT2 ( ortholog_one2one ) Rat_ Wnt2 ( ortholog_one2one ) Rabbit_ WNT2 ( ortholog_one2one ) |
| Ohnologs | WNT2B, WNT3A, WNT7A |
| Paralogs | WNT5A, WNT6, WNT3, WNT4, WNT2B, WNT9B, WNT16, WNT8B, WNT11, WNT3A, WNT7B, WNT5B, WNT10A, WNT9A, WNT7A, WNT10B, WNT1, WNT8A |
| Tissue | placenta |
| Tissue Specificity | Expressed in brain in the thalamus, in fetal and adult lung and in placenta. {ECO:0000269|PubMed:11449391}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs145839592 rs1051751 rs148046128 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000305}. Secreted {ECO:0000269|PubMed:20018874}. |
| Mouse PG classification | NA |
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