| Gene Information | |
|---|---|
| Gene Name | TRAK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 914 |
| Protein Names | Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000115993 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O60296 |
| Gene Card | TRAK2 |
| Uniprot ID | O60296 |
| Pfam | PF04849; PF12448 |
| In ASD | no |
| Allosteric Prediction | yes (0.548341175) |
| Ortholog in Animals | Alpaca_ TRAK2 ( ortholog_one2one ) Dog_ TRAK2 ( ortholog_one2one ) GuineaPig_ TRAK2 ( ortholog_one2one ) Macaque_ TRAK2 ( ortholog_one2one ) Mouse_ Trak2 ( ortholog_one2one ) Pig_ TRAK2 ( ortholog_one2one ) Rat_ Trak2 ( ortholog_one2one ) Rabbit_ TRAK2 ( ortholog_one2one ) |
| Ohnologs | HAP1, TRAK1 |
| Paralogs | HAP1, TRAK1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest expression in heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13022344 rs2244438 rs34594680 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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