| Gene Information | |
|---|---|
| Gene Name | FASTKD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 710 |
| Protein Names | FAST kinase domain-containing protein 2, mitochondrial |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000118246 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NYY8 |
| Gene Card | FASTKD2 |
| Uniprot ID | Q9NYY8 |
| Pfam | PF06743; PF08368; PF08373 |
| In ASD | no |
| Allosteric Prediction | no (-0.997562769) |
| Ortholog in Animals | Alpaca_ FASTKD2 ( ortholog_one2one ) Dog_ FASTKD2 ( ortholog_one2one ) GuineaPig_ FASTKD2 ( ortholog_one2one ) Macaque_ FASTKD2 ( ortholog_one2one ) Mouse_ Fastkd2 ( ortholog_one2one ) Pig_ FASTKD2 ( ortholog_one2one ) Rat_ Fastkd2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TBRG4, FASTK, FASTKD3, FASTKD5, FASTKD1 |
| Tissue | NA |
| Tissue Specificity | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle and thyroid. {ECO:0000269|PubMed:20869947}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3762568 rs13003768 |
| Subcellular location [CC] | Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:20869947, ECO:0000269|PubMed:25683715}. Mitochondrion matrix {ECO:0000305|PubMed:18771761}. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. {ECO:0000269|PubMed:25683715}. |
| Mouse PG classification | NA |
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