| Gene Information | |
|---|---|
| Gene Name | KIAA0566 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1499 |
| Protein Names | Phospholipid-transporting ATPase VA (EC 7.6.2.1) (ATPase class V type 10A) (Aminophospholipid translocase VA) (P4-ATPase flippase complex alpha subunit ATP10A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O60312 |
| Gene Card | ATP10A |
| Uniprot ID | O60312 |
| Pfam | PF16212; PF16209 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in kidney, followed by lung, brain, prostate, testis, ovary and small intestine. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs763246380 rs17116056 rs56724944 rs2066703 rs2066704 rs17555920 rs2076742 rs2076744 rs2076745 rs2076746 rs3816800 rs9324127 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:21914794, ECO:0000269|PubMed:25947375, ECO:0000269|PubMed:30530492}; Multi-pass membrane protein {ECO:0000269|PubMed:21914794}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21914794, ECO:0000269|PubMed:25947375}. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not that of TMEM30B. |
| Mouse PG classification | NA |
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