| Gene Information | |
|---|---|
| Gene Name | HACD4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 232 |
| Protein Names | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 4) (HACD4) (Protein-tyrosine phosphatase-like A domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000188921 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q5VWC8 |
| Gene Card | HACD4 |
| Uniprot ID | Q5VWC8 |
| Pfam | PF04387 |
| In ASD | no |
| Allosteric Prediction | no (-1.345060461) |
| Ortholog in Animals | Alpaca_ HACD4 ( ortholog_one2one ) Dog_ HACD4 ( ortholog_one2one ) GuineaPig_ HACD4 ( ortholog_one2one ) Macaque_ HACD4 ( ortholog_one2one ) Mouse_ Hacd4 ( ortholog_one2one ) Pig_ HACD4 ( ortholog_one2one ) Rat_ Hacd4 ( ortholog_one2one ) Rabbit_ HACD4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HACD3, HACD1, HACD2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in leukocytes, and low expression in heart, spleen, kidney, and placenta. {ECO:0000269|PubMed:18554506}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2298260 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18554506}; Multi-pass membrane protein {ECO:0000269|PubMed:18554506}. |
| Mouse PG classification | NA |
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