| Gene Information | |
|---|---|
| Gene Name | CHMP5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 219 |
| Protein Names | Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000086065 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NZZ3 |
| Gene Card | CHMP5 |
| Uniprot ID | Q9NZZ3 |
| Pfam | PF03357 |
| In ASD | no |
| Allosteric Prediction | no (-1.402054165) |
| Ortholog in Animals | Alpaca_ CHMP5 ( ortholog_one2one ) Dog_ CHMP5 ( ortholog_one2one ) GuineaPig_ CHMP5 ( ortholog_one2one ) Macaque_ CHMP5 ( ortholog_one2one ) Mouse_ Chmp5 ( ortholog_one2one ) Pig_ CHMP5 ( ortholog_one2one ) Rat_ Chmp5 ( ortholog_one2one ) Rabbit_ CHMP5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHMP4A, CHMP4B, CHMP7, CHMP4C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001445(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LXM (NMR - ) 3ULY (X-ray 2.60A ) 3UM0 (X-ray 3.10A ) 3UM1 (X-ray 2.71A ) 3UM2 (X-ray 2.59A ) 4TXR (X-ray 1.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:15644320}. Endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Midbody {ECO:0000269|PubMed:17853893}. Note=Localizes to the midbody of dividing cells (PubMed:17853893). Localized in two distinct rings on either side of the Flemming body (PubMed:17853893). {ECO:0000269|PubMed:17853893}. |
| Mouse PG classification | NA |
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