| Gene Information | |
|---|---|
| Gene Name | H6PD |
| Organism | Homo sapiens (Human) |
| Gene Length | 791 |
| Protein Names | GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase) (GDH) (EC 1.1.1.47) (Glucose-6-phosphate dehydrogenase) (EC 1.1.1.363); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)] |
| Target Name | gdh/6pgl endoplasmic bifunctional protein |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000049239 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O95479 |
| Gene Card | H6PD |
| Uniprot ID | O95479 |
| Pfam | PF02781; PF00479; PF01182 |
| In ASD | no |
| Allosteric Prediction | yes (0.461669149) |
| Ortholog in Animals | Alpaca_ H6PD ( ortholog_one2one ) Dog_ H6PD ( ortholog_one2one ) GuineaPig_ H6PD ( ortholog_one2one ) Macaque_ H6PD ( ortholog_one2one ) Mouse_ H6pd ( ortholog_one2one ) Pig_ H6PD ( ortholog_one2one ) Rat_ H6pd ( ortholog_one2one ) Rabbit_ H6PD ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | G6PD |
| Tissue | NA |
| Tissue Specificity | Present in most tissues examined, strongest in liver. {ECO:0000269|PubMed:10349511}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.071429(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34603401 rs35525021 rs387907167 rs6688832 rs35404275 rs17368528 |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000305|PubMed:18628520}. |
| Mouse PG classification | LPG |
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