Gene Information
Gene NameDNAAF5
OrganismHomo sapiens (Human)
Gene Length855
Protein NamesDynein axonemal assembly factor 5 (HEAT repeat-containing protein 2)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000164818 )
Evolutionary StageEukaryota
AlphaFoldDBQ86Y56
Gene CardDNAAF5
Uniprot IDQ86Y56
PfamNA
In ASDno
Allosteric Predictionno (-0.857824116)
Ortholog in AnimalsDog_ DNAAF5 ( ortholog_one2one )
GuineaPig_ DNAAF5 ( ortholog_one2one )
Macaque_ DNAAF5 ( ortholog_one2one )
Mouse_ Dnaaf5 ( ortholog_one2one )
Pig_ DNAAF5 ( ortholog_one2one )
Rat_ Dnaaf5 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in nasal epithelium and lung epithelium by ciliated cells (at protein level). {ECO:0000269|PubMed:23040496}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002101(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs73258248  rs4720951  rs3922641  rs397514561 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:23040496, ECO:0000269|PubMed:25232951}. Dynein axonemal particle {ECO:0000269|PubMed:23040496, ECO:0000269|PubMed:25232951}. Note=Observed only in the cytoplasm of ciliated cells and absent from cilia. {ECO:0000269|PubMed:23040496, ECO:0000269|PubMed:25232951}.
Mouse PG classificationNA
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