Gene Information
Gene NamePRRG1
OrganismHomo sapiens (Human)
Gene Length218
Protein NamesTransmembrane gamma-carboxyglutamic acid protein 1 (Proline-rich gamma-carboxyglutamic acid protein 1) (Proline-rich Gla protein 1)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000130962 )
Evolutionary StageVertebrata
AlphaFoldDBO14668
Gene CardPRRG1
Uniprot IDO14668
PfamPF00594
In ASDno
Allosteric Predictionno (-1.27828513)
Ortholog in AnimalsAlpaca_ PRRG1 ( ortholog_one2one )
Dog_ PRRG1 ( ortholog_one2one )
GuineaPig_ PRRG1 ( ortholog_one2one )
Mouse_ Prrg1 ( ortholog_one2one )
Pig_ PRRG1 ( ortholog_one2one )
Rat_ Prrg1 ( ortholog_one2one )
Rabbit_ PRRG1 ( ortholog_one2one )
OhnologsPRRG2
ParalogsOVCH2, PRRG4, PRRG3
TissueNA
Tissue SpecificityHighly expressed in the spinal cord.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}.
Mouse PG classificationNA
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