Gene Information
Gene NameTRADD
OrganismHomo sapiens (Human)
Gene Length312
Protein NamesTumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000102871 )
Evolutionary StageVertebrata
AlphaFoldDBQ15628
Gene CardTRADD
Uniprot IDQ15628
PfamPF00531; PF09034
In ASDno
Allosteric Predictionyes (0.384753674)
Ortholog in AnimalsAlpaca_ TRADD ( ortholog_one2one )
Dog_ TRADD ( ortholog_one2one )
GuineaPig_ TRADD ( ortholog_one2one )
Macaque_ TRADD ( ortholog_one2one )
Mouse_ Tradd ( ortholog_one2one )
Pig_ TRADD ( ortholog_one2one )
Rat_ Tradd ( ortholog_one2one )
Rabbit_ TRADD ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityFound in all examined tissues. {ECO:0000269|PubMed:7758105}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.358012(Rat);0.053333(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1F2H  (NMR  1F3V  (X-ray  2.00A  5XME  (NMR  6AC0  (X-ray  1.45A  7CSQ  (NMR 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000250|UniProtKB:Q3U0V2}. Cytoplasm {ECO:0000269|PubMed:11684708}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11684708}. Note=Shuttles between the cytoplasm and the nucleus. {ECO:0000250|UniProtKB:Q3U0V2}.
Mouse PG classificationNA
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