Gene Information
Gene NameCD300LD
OrganismHomo sapiens (Human)
Gene Length194
Protein NamesCMRF35-like molecule 5 (CLM-5) (CD300 antigen-like family member D) (CMRF35-A4) (CD antigen CD300d)
Target NameNA
Target TypeNA
Gene Age36 ( ENSG00000204345 )
Evolutionary StageVertebrata
AlphaFoldDBQ6UXZ3
Gene CardCD300LD
Uniprot IDQ6UXZ3
PfamPF07686
In ASDno
Allosteric Predictionno (-0.947915195)
Ortholog in AnimalsAlpaca_ CD300LD ( ortholog_one2one )
Mouse_ Cd300a ( ortholog_many2many )
OhnologsNA
ParalogsTREML1, FCAMR, TMIGD3, CD300H, CD300LF, CD300C, CD300LG, CD300A, FCMR, PIGR, CD300E, TREM2, CD300LB
TissueNA
Tissue SpecificityExpression seems restricted to cells of myeloid lineage. {ECO:0000269|PubMed:22291008}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs493430  rs783239 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:22291008};
Single-pass type I membrane protein {ECO:0000269|PubMed:22291008}. Note=Cell surface localization requires the ITAM-bearing Fc receptor FCER1G to overcome ER retention.
Mouse PG classificationNA
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